Factitious hypoglycaemia: chlorpropamide self-administration by a non-diabetic.

Hyperinsulinaemic hypoglycaemia due to chlorpropamide-induced nesidioblastosis.

A 25 year old woman suffering from recurrent attacks of hypoglycaemia underwent a laparotomy for suspected insulinoma. No tumour was found, but histology showed islet cell hyperplasia and nesidioblastosis. Although these changes have been reported as a cause of hypoglycaemia in infants, they are only rarely the cause of hypoglycaemia in adults; in the present case they were found to be the resu...

C-peptide suppression test and sulphonylurea-induced factitious hypoglycaemia.

Characterisation of antibodies to insulin to help diagnose factitious hypoglycaemia.

Accidental gonococcal infection of the eyes in children.

The differential diagnosis, which lay between insulinoma, extrapancreatic tumour, hepatic disease, and endocrine disease, was narrowed after investigation to an insulinoma or an extrapancreatic tumour. Normally blood insulin values would have established the diagnosis, but they would have been misleading in this case and could have led to a pancreatectomy. Cases such as this fulfil all the crit...

Six cases of (severe) hypoglycaemia associated with gabapentin use in both diabetic and non-diabetic patients.

Gabapentin, a gamma-aminobutyric acid (GABA) analogue, is a commonly used drug in the treatment of partial epilepsy and peripheral neuropathic pain. Although the exact mechanism of action has not been elucidated, the binding site has been identified as the alpha2-delta subunit of the voltage-gated calcium channels in the neocortex and hippocampal regions of the brain [1]. Hypoglycaemia in diabe...